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Creatine kinase, also known as phosphocreatine kinase or creatine phosphokinase, is an enzyme or type of protein that is found in several tissue types of the human. I was wondering, does anyone have ear pain without any ear problems? i have been checked out by neuro, ent and gp and nothing. i’m wondering if i have tmj but i don’t. I have severe muscle pain, stiffness, fatigue, joints popping constantly, im 28 whats wrong?.